Methyl 3-bromoindazole-5-...
Methyl 3-bromo-1H-indazole-5-carboxylate
CAS: 1086391-06-1
Molecular Formula: C9H7BrN2O2
Methyl 3-bromoindazole-5-... - Names and Identifiers
Methyl 3-bromoindazole-5-... - Physico-chemical Properties
| Molecular Formula | C9H7BrN2O2 |
| Molar Mass | 255.07 |
| Density | 1.709 |
| Boling Point | 399.7±22.0 °C(Predicted) |
| pKa | 10.62±0.40(Predicted) |
| Storage Condition | 2-8℃ |
| Sensitive | Irritant |
| MDL | MFCD11045401 |
Methyl 3-bromoindazole-5-... - Introduction
Methyl 3-bromo-1H-indazole-5-carboxylate is an organic compound with a molecular formula of C, H BrNO, and a relative molecular mass of 229.04. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: colorless or light yellow liquid
-Melting point:-36 ℃
-Boiling point: 208-209 ℃
-Density: 1.665 g/mL
-Solubility: Soluble in alcohol, ether and organic solvents, insoluble in water
Use:
3-Bromo-1H-indazole-5-carboxylic acid methyl ester is commonly used as a reagent and intermediate in organic synthesis. Its main uses include the following aspects:
-as a pesticide intermediate, used in the synthesis of pyrazole, triadimefon and other pesticides;
-as drug intermediates, used to synthesize some compounds with anti-tumor, anti-virus and anti-fungal activity;
-for the preparation of indazole dyes, can be used in paper, plastics, textiles and other fields;
-used in the synthesis of organic synthesis reaction catalyst, ligand, etc.
Preparation Method:
3-Bromo -1H-indazole -5-carboxylic acid methyl ester preparation method is more, a commonly used method is as follows:
It is prepared by reacting methyl 2-bromo-1H-indazole-5-carboxylate with iodine or bromine under basic conditions.
Safety Information:
3-Bromo-1H-indazole-5-carboxylic acid methyl ester is an organic solvent and intermediate with high toxicity and should be used with caution. During use, the following safety precautions should be paid attention:
-Avoid contact with skin, eyes and respiratory tract to prevent inhalation, ingestion or inhalation of dust;
-the use of the need to wear protective gloves, glasses, protective masks and other personal protective equipment;
-Operate in a well-ventilated place and keep away from open flames and heat sources;
-storage should be sealed, away from acids, alkalis and oxidants.
Please note that the above content is for reference only, and should be combined with the actual situation and relevant experimental operation manuals.
Nature:
-Appearance: colorless or light yellow liquid
-Melting point:-36 ℃
-Boiling point: 208-209 ℃
-Density: 1.665 g/mL
-Solubility: Soluble in alcohol, ether and organic solvents, insoluble in water
Use:
3-Bromo-1H-indazole-5-carboxylic acid methyl ester is commonly used as a reagent and intermediate in organic synthesis. Its main uses include the following aspects:
-as a pesticide intermediate, used in the synthesis of pyrazole, triadimefon and other pesticides;
-as drug intermediates, used to synthesize some compounds with anti-tumor, anti-virus and anti-fungal activity;
-for the preparation of indazole dyes, can be used in paper, plastics, textiles and other fields;
-used in the synthesis of organic synthesis reaction catalyst, ligand, etc.
Preparation Method:
3-Bromo -1H-indazole -5-carboxylic acid methyl ester preparation method is more, a commonly used method is as follows:
It is prepared by reacting methyl 2-bromo-1H-indazole-5-carboxylate with iodine or bromine under basic conditions.
Safety Information:
3-Bromo-1H-indazole-5-carboxylic acid methyl ester is an organic solvent and intermediate with high toxicity and should be used with caution. During use, the following safety precautions should be paid attention:
-Avoid contact with skin, eyes and respiratory tract to prevent inhalation, ingestion or inhalation of dust;
-the use of the need to wear protective gloves, glasses, protective masks and other personal protective equipment;
-Operate in a well-ventilated place and keep away from open flames and heat sources;
-storage should be sealed, away from acids, alkalis and oxidants.
Please note that the above content is for reference only, and should be combined with the actual situation and relevant experimental operation manuals.
Last Update：2024-04-10 22:41:03
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Product Name: Methyl3-bromo-1H-indazole-5-carboxylate Request for quotationCAS: 1086391-06-1
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Methyl 3-bromo-1H-indazole-5-carboxylate Visit Supplier Webpage Request for quotationCAS: 1086391-06-1
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: methyl 3-bromo-1H-indazole-5-carboxylate Visit Supplier Webpage Request for quotationCAS: 1086391-06-1
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
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